In the germ line, PAL-1 synthesis is prevented by the PUF-8 protein, which binds to the 3′ UTR of pal-1 mRNA and blocks its translation.

TLS Online TPP Program

#Id: 2382

#Unit 3. Fundamental Processes

Prp2 is responsible for the activation of the spliceosome Prp22 helps the release of the mature mRNA from the spliceosome

TLS Online TPP Program

#Id: 2383

#Unit 3. Fundamental Processes

Prp22 helps the release of the mature mRNA from the spliceosome, makes splicing irreversible.

TLS Online TPP Program

#Id: 2384

#Unit 3. Fundamental Processes

More than 90% of the genes expressed in mammals are alternatively spliced

TLS Online TPP Program

#Id: 2385

#Unit 3. Fundamental Processes

 Five ways to splice an RNA

TLS Online TPP Program

#Id: 2386

#Unit 3. Fundamental Processes

Steric Hindrance and Combinations of Major and Minor Splice Sites are major reasons behind alternative splicing (Mutually Exclusive Splicing) 

TLS Online TPP Program

#Id: 2387

#Unit 3. Fundamental Processes

Alternative splicing is often associated with weak splice sites.