type I is stating something which is not present or a false hit.

TLS Online TPP Program

#Id: 7169

#Unit 5. Developmental Biology

The major candidate for the factor that forms the Nieuwkoop center was β-catenin (This multifunctional protein also proved to be a key player in the formation of the dorsal amphibian tissues)

TLS Online TPP Program

#Id: 7170

#Unit 5. Developmental Biology

During first cleavage, GBP, Dsh, and Wnt11 are brought into the future dorsal section of the embryo protect β-catenin

TLS Online TPP Program

#Id: 7171

#Unit 5. Developmental Biology

During cleavage, β-catenin enters the nuclei and binds with Tcf3 to form a transcription factor that activates genes encoding proteins Siamois and Twin.

TLS Online TPP Program

#Id: 7172

#Unit 5. Developmental Biology

Siamois and Twin interact in the organizer with the Smad2 transcription factor activated by vegetal TGF-β family members (Nodal-related proteins, Vg1, activin)

TLS Online TPP Program

#Id: 7173

#Unit 5. Developmental Biology

Twin and Siamois encode homeodomain transcription factors and are expressed in the organizer

TLS Online TPP Program

#Id: 7174

#Unit 5. Developmental Biology

High β-catenin + Nodal related high + Veg T, Vg1 = Organizer