level of significance defines whether the null hypothesis is assumed to be accepted or rejected. It is expected to identify if the result is statistically significant for the null hypothesis to be false or rejected.

TLS Online TPP Program

#Id: 7496

#Unit 4. Cell Communication and Cell Signaling

Only three of the proteins implicated in V(D)J recombination are unique to lymphocytes: RAG1, RAG2, and Terminal deoxynucleotidyl Transferase (TdT)

TLS Online TPP Program

#Id: 7497

#Unit 4. Cell Communication and Cell Signaling

Recombination between the D and a JH gene segment occur during pre-pro-B cell to the early pro-B-cell stage.

TLS Online TPP Program

#Id: 7498

#Unit 4. Cell Communication and Cell Signaling

Recombination between the VH and D-JH segments follows during the pro-B-cell stage.

TLS Online TPP Program

#Id: 7499

#Unit 4. Cell Communication and Cell Signaling

VpreB and λ5 (called a surrogate light chain), to form a pre-B-cell receptor.

TLS Online TPP Program

#Id: 7500

#Unit 4. Cell Communication and Cell Signaling

Light-chain recombination occurs at the small pre-B-cell stage of B-cell development.

TLS Online TPP Program

#Id: 7501

#Unit 4. Cell Communication and Cell Signaling

Site of DNA cleavage - Recombination Signal Sequence (RSS)