Only fully methylated origins can initiate replication;

hemimethylated daughter origins cannot be used again until they have been restored to the fully methylated state.

TLS Online TPP Program

#Id: 3177

#Unit 3. Fundamental Processes

Mitochondrial segregation to daughter cells is also stochastic.

TLS Online TPP Program

#Id: 3178

#Unit 3. Fundamental Processes

When there are mtDNAs with allelic variations in the same cell, called heteroplasmy (either because of inheritance from different parents or because of mutation).

TLS Online TPP Program

#Id: 3179

#Unit 3. Fundamental Processes

Replication of mtDNA may be stochastic because there is no control over which particular copies are replicated, so that in any cycle some mtDNA molecules may replicate more times than others.

TLS Online TPP Program

#Id: 3180

#Unit 3. Fundamental Processes

A mitochondrion divides by developing a ring around the organelle that constricts to pinch it into two halves. The mechanism is similar in principle to that involved in bacterial division.

TLS Online TPP Program

#Id: 3181

#Unit 3. Fundamental Processes

The apparatus that is used in plant cell mitochondria is similar to that used in bacteria and uses a homolog of the bacterial protein FtsZ. 

TLS Online TPP Program

#Id: 3182

#Unit 3. Fundamental Processes

The molecular apparatus is different in animal cell mitochondria and uses the protein dynamin, which is involved in formation of membranous vesicles