Two to four monomers of DnaAATP bind at the origin, and after release of DiaA, they recruit two “pre-priming” complexes of the DnaB helicase bound to DnaC-ATP, so that there is one DnaB–DnaC-ATP complex for each of the two (bidirectional) replication forks.

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#Id: 1550

#Unit 2. Cellular Organization

Kinesin-1 powers anterograde transport of vesicles down axons toward the (+) ends of microtubules.

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#Id: 4746

#Unit 5. Developmental Biology

Sperm microtubules contacts the cortical cytoplasm and initiates cytoplasmic movements that push the male pronucleus to the nearest end of the oblong oocyte.

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#Id: 7879

#Unit 2. Cellular Organization

The curvature of the crista junctions is due to a protein complex called MICOS (mitochondrial contact site and cristae organizing system).

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#Id: 9075

#Unit 4. Cell Communication and Cell Signaling

Active PDE hydrolyzes cAMP, driving cAMP levels back to basal levels.

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#Id: 8617

#Unit 2. Cellular Organization

Wee1 kinase Inhibits CDKs in all organisms