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TLS Online TPP Program

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Anticlotting mechanisms  The tendency of blood to clot is balanced in vivo by reactions that prevent clotting inside the blood vessels, break down any clots that 
do form, or both.


#Unit 7. System Physiology – Animal #Blood and circulation #Part B Pointers
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TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

FADD can also be directly activated by binding to TRADD in RIPK1-independent apoptosis activation.

TLS Online TPP Program

#Id: 10555

#Unit 4. Cell Communication and Cell Signaling

Caspase-8 cleaves and activates several effector caspases, caspase-3, 6, 7 to complete apoptotic cell death.

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Intrinsic apoptosis pathway
Caspase-8 cleaves the BH3-interacting-domain death agonist (Bid), resulting tBid fragment

TLS Online TPP Program

#Id: 10557

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 10558

#Unit 4. Cell Communication and Cell Signaling

tBid fragment binds to Bcl-2 on the outer mitochondrial membrane, leading to the dissociation of Bak and Bax and release of cytochrome c into the cytosol

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