Antithrombin III is a circulating protease inhibitor that binds to serine proteases in the coagulation system, blocking their activity as clotting factors.

TLS Online TPP Program

#Id: 4023

#Unit 2. Cellular Organization

In most regions, the fibers are much less densely packed than in the mitotic chromosome. This material is called euchromatin. It has a relatively dispersed appearance in the nucleus and occupies most of the nuclear region.

TLS Online TPP Program

#Id: 3648

#Unit 3. Fundamental Processes

In ValRS, the side chain of Asp 279 protrudes into the editing active site, where it hydrogen-bonds with the hydroxyl group of threonine. The isosteric (having the same shape) valine lacks this hydroxyl group and is thereby excluded from the editing pocket.

TLS Online TPP Program

#Id: 8643

#Unit 2. Cellular Organization

When E2Fs are bound to Rb, not only are they transcriptionally inactive, but they also function to repress transcription by recruiting chromatin-modifying enzymes that promote deacetylation and methylation of specific histone lysines.

TLS Online TPP Program

#Id: 9082

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 1479

#Unit 4. Cell Communication and Cell Signaling

Characterization of the disease-causing deletion showed that the absence of two miRNAs, miR-15-a and miR-16-1, causes chronic lymphocytic leukemia (CLL)