Nurturing Life Sciences
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#Unit 3. Fundamental Processes
UACUAAC is branch point sequence for U2 type intronsCCUUAAC is branch point sequence for U12 type introns
UACUAAC is branch point sequence for U2 type introns
CCUUAAC is branch point sequence for U12 type introns
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Prp8, a large scaffold protein that directly contacts both the 5’ and 3’ splice sites within the spliceosome.
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Prp5 is critical for U2 binding
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Brr2 facilitates U1 and U4 release
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Prp2 is responsible for the activation of the spliceosome Prp22 helps the release of the mature mRNA from the spliceosome
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Prp22 helps the release of the mature mRNA from the spliceosome, makes splicing irreversible.