The innermost zone of the cortex, zona reticularis, and the middle zone, zona fasciculata, synthesize and secrete glucocorticoids and adrenal androgens.

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Responder, 

the cell or tissue being induced.

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Cells of the responding tissue must have both, 

A receptor protein for the inducing factor 

The ability to respond to the signal

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Competence 

The ability to respond to a specific inductive signal

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Reciprocal induction occurs when the two interacting tissues are both inducers and are competent to respond to each other’s signals.

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The development of the vertebrate eye is a classic example used to describe the modus operandi of tissue organization via intercellular interactions.

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#Unit 5. Developmental Biology

In the initiation of the vertebrate eyes, paired regions of the brain bulges (optic vesicles, act as inducer) out and approach the surface ectoderm (act as responder) of the head.