TLS Online TPP Program

#Id: 6780

#Unit 3. Fundamental Processes

The mechanism of spacer sequence acquisition is as 

Each new spacer sequence is inserted next to the leader sequence, with the consequence that the array is a temporal record of acquisitions past. The sequence destined to become spacer is, within the phage genome, known as a “proto-spacer” and lies adjacent to a PAM sequence

TLS Online TPP Program

#Id: 8459

#Unit 1. Molecules and their Interaction Relevant to Biology

Five types of constraints affect the stability of an  helix: 

(1) the intrinsic propensity of an amino acid residue to form an  helix; 

(2) the interactions between R groups, particularly those spaced three (or four) residues apart; 

(3) the bulkiness of adjacent R groups; 

(4) the occurrence of Pro and Gly residues; and 

(5) interactions between amino acid residues at the ends of the helical segment and the electric dipole inherent to the  helix.

TLS Online TPP Program

#Id: 9764

#Unit 6. System Physiology – Plant

Perception of MAMPs or DAMPs by cell surface PRRs is called Pathogen Triggered Immunity

TLS Online TPP Program

#Id: 4769

#Unit 5. Developmental Biology

Specification of the MS cell begins with maternal SKN-1 activating the genes encoding GATA transcription factors MED-1 and MED-2

TLS Online TPP Program

#Id: 3511

#Unit 2. Cellular Organization

Introns may more freely accumulate point substitutions and other changes due to no selection pressure.  Introns evolve or accumulate mutations/changes much more rapidly than exons