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TLS Online TPP Program

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The cI gene is transcribed from PRE when establishing lysogeny and from PRM when maintaining that state. 
PR controls not only lytic genes, but also expression of cII and is thus important in lysogeny as well as lytic development. PL which controls many lytic genes, also controls the cIII gene which helps establish lysogeny

#Unit 2. Cellular Organization #Phage Strategies #Part B Pointers
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TLS Online TPP Program

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#Unit 3. Fundamental Processes

POT1 binding to single-stranded telomere DNA inhibits telomere activity.

TLS Online TPP Program

#Id: 684

#Unit 3. Fundamental Processes

Structure of growing Telomere is potential target for DSBR

TLS Online TPP Program

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#Unit 3. Fundamental Processes

Attempts to repair telomeres in the DSBR manner as double-stranded DNA breaks would lead to chromosome fusion events, which eventually result in random chromosome breaks.

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#Unit 3. Fundamental Processes

 Shelterin proteins bound at the telomere distinguish telomeres from other DNA ends in the cell prevents telomeres from normal DSBR

TLS Online TPP Program

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#Unit 3. Fundamental Processes

Elimination of Shelterin leads to the recognition of the telomeres as normal DNA breaks.

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#Unit 3. Fundamental Processes

Telomeres form a looped structure in the cell called as t-loop

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