Genes whose products are involved in controlling the fidelity of DNA synthesis during either replication or repair may be identified by mutations that have a mutator phenotype called as mut system of repair or MMR

TLS Online TPP Program

#Id: 6885

#Unit 3. Fundamental Processes

DNA methylation and macroH2A contribute to the stable repression of the inactive X chromosome  A. Wutz and J. Gribnau, Curr. Opin. Genet. Dev. 17 (2007): 387–393. inactive specific transcript), which is stably expressed only on the inactive X chromosome.

TLS Online TPP Program

#Id: 10497

#Unit 4. Cell Communication and Cell Signaling

Necrosis

occurs when cells are subjected to injury or excessive stresses, such as heat, absence of oxygen, or infection

by pathogens & marked by swelling and bursting of cells with release of their contents.

TLS Online TPP Program

#Id: 2413

#Unit 3. Fundamental Processes

TRCF binds to double-stranded DNA upstream of the polymerase and uses the ATPase motor to translocate along the DNA until it encounters the stalled RNA polymerase.

TLS Online TPP Program

#Id: 9918

#Unit 4. Cell Communication and Cell Signaling

Innate response elements commonly engaged by encounter with viral PAMPs, such as secretion of type I interferons, inflammasome and NK-cell activation, as well as IL-12 production.

TLS Online TPP Program

#Id: 8531

#Unit 2. Cellular Organization

Dynamic instability 

Rapid interconversion between a growing and shrinking state, at a uniform free tubulin concentration