The deamination generates a G-T/C-T mismatch pair, MutL and MutS remove T from both G-T and C-T mismatches.

TLS Online TPP Program

#Id: 2584

#Unit 7. System Physiology – Animal

There are two components for Cl− reabsorption:

Transcellular

Paracellular

TLS Online TPP Program

#Id: 2585

#Unit 7. System Physiology – Animal

Function of the two exchangers is to transport NaCl from the lumen into the cell:

Na+-H+ exchanger

Cl−-formate− anion exchanger

TLS Online TPP Program

#Id: 2586

#Unit 7. System Physiology – Animal

The proximal tubule is an important site for secretion of organic acids and bases such as bile salts, oxalate, urate, and catecholamines.

TLS Online TPP Program

#Id: 2649

#Unit 7. System Physiology – Animal

Thin descending and thin ascending segments, have thin epithelial membranes with no brush borders, few mitochondria, & minimal levels of metabolic activity.

TLS Online TPP Program

#Id: 2650

#Unit 7. System Physiology – Animal

Descending part of the thin segment is highly permeable to water and moderately permeable to most

Solutes (urea and sodium).

TLS Online TPP Program

#Id: 2651

#Unit 7. System Physiology – Animal

In the Descending part of the thin segment 

About 20 percent of the filtered water is reabsorbed