TLS Online TPP Program

#Id: 7460

#Unit 5. Developmental Biology

Ammonia inhibits PKA by indirectly activating cAMP hydrolysis via DhkC-RdeA mediated phosphorylation of RegA.

TLS Online TPP Program

#Id: 7461

#Unit 5. Developmental Biology

Binding of Spore differentiation factor 2 activates the histidine phosphatase activity of DhkA (histidine phosphatase A)

TLS Online TPP Program

#Id: 7462

#Unit 5. Developmental Biology

Histidine phosphatase activity of DhkA causes inactivation of RegA, the accumulation of cAMP and PKA activation, causes spore maturation.

TLS Online TPP Program

#Id: 7463

#Unit 5. Developmental Biology

TLS Online TPP Program

#Id: 7464

#Unit 5. Developmental Biology

In prespore cells, PKA activation occurs by signalling cascade that is activated by SDF-3, which triggers the synthesis of GABA

TLS Online TPP Program

#Id: 7465

#Unit 5. Developmental Biology

Secreted GABA then acts on prestalk cells to induce the cell-surface exposure of the serine protease domain of the ABC transporter TagC.