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RNA polymerase I requires two ancillary transcription factors to recognize the promoter sequence. The factor that binds to the core promoter is SL1 which consists of four protein subunits. SL1 has primary responsibility for RNA polymerase recruitment









#Unit 3. Fundamental Processes #Eukaryotic Transcription #Part B Pointers
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TLS Online TPP Program

#Id: 6527

#Unit 7. System Physiology – Animal

The pancreas is composed of two major types of tissues, as: 
the acini
the islets of Langerhans

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#Id: 6528

#Unit 7. System Physiology – Animal

Insulin, 
synthesized and secreted 
by the β cells




TLS Online TPP Program

#Id: 6529

#Unit 7. System Physiology – Animal

Insulin has an AB heterodimer structure with 
One intrachain (A6-A11) 
Two interchain disulfide bridges (A7-B7 and A20-B19)



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#Unit 7. System Physiology – Animal


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#Id: 6531

#Unit 7. System Physiology – Animal

Insulin secretion by the pancreatic beta cells in response to increased blood glucose concentration




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#Id: 6532

#Unit 7. System Physiology – Animal

The beta cells have a large number of glucose transporters that permit a rate of glucose influx that is proportional to the blood concentration in the physiological range



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