RNA polymerase I requires two ancillary transcription factors to recognize the promoter sequence. The factor that binds to the core promoter is SL1 which consists of four protein subunits. SL1 has primary responsibility for RNA polymerase recruitment

TLS Online TPP Program

#Id: 3109

#Unit 3. Fundamental Processes

Replication is unidirectional when a single replication fork is created at an origin.

TLS Online TPP Program

#Id: 3110

#Unit 3. Fundamental Processes

Replication is bidirectional when an origin creates two replication forks that move in opposite directions.

TLS Online TPP Program

#Id: 3111

#Unit 3. Fundamental Processes

The replicated region appears as a replication bubble within the nonreplicated DNA. 

TLS Online TPP Program

#Id: 3112

#Unit 3. Fundamental Processes

A replication bubble forms a θ structure in circular DNA.

TLS Online TPP Program

#Id: 3114

#Unit 3. Fundamental Processes

Bacterial replicons are usually circles that replicate bidirectionally from a single origin.

TLS Online TPP Program

#Id: 3115

#Unit 3. Fundamental Processes

The origin of E. coli, oriC, is 245 bp in length.