The glucagon receptor, found primarily on liver cells, is coupled to the Gαs protein, to activate adenylyl cyclase and increase intracellular cAMP

TLS Online TPP Program

#Id: 6859

#Unit 3. Fundamental Processes

Chromatin remodeling is tool for Epigenetic effects which result from modification of a nucleic acid after it has been synthesized or by the perpetuation of protein structures.

TLS Online TPP Program

#Id: 6860

#Unit 3. Fundamental Processes

Position effect variegation (PEV) 

TLS Online TPP Program

#Id: 6861

#Unit 3. Fundamental Processes

In Drosophila, an example of position effect variegation in the fly eye. 

TLS Online TPP Program

#Id: 6862

#Unit 3. Fundamental Processes

Some of the regions in the eye lack color, whereas others are red. This is because the white gene (required to develop red pigment) was inactivated by adjacent heterochromatin in some cells, but remained active in others.

TLS Online TPP Program

#Id: 6863

#Unit 3. Fundamental Processes

Su(var) for genes

whose products act to suppress variegation and E(var) for genes whose products enhance variegation.

active in others.

TLS Online TPP Program

#Id: 6864

#Unit 3. Fundamental Processes

Su(var) mutations lie in genes whose products are needed for the formation of heterochromatin such as HDAC, HMT.