TLS Online TPP Program

#Id: 8375

#Unit 2. Cellular Organization

Ca2+ dependence of vertebrate skeletal muscle contraction, depends on :

action potential

specialized accessory proteins Tropomyosin,

Troponin (T, I, and C)

TLS Online TPP Program

#Id: 8376

#Unit 2. Cellular Organization

Myosin 

Actin-based motors powered by ATP hydrolysis.

TLS Online TPP Program

#Id: 8377

#Unit 2. Cellular Organization

Myosins have 

Motor head domain

Lever-arm neck domain

Cargo-binding tail domain

TLS Online TPP Program

#Id: 8378

#Unit 2. Cellular Organization

The first myosin discovered

Myosin II, was isolated from skeletal muscle.

TLS Online TPP Program

#Id: 8379

#Unit 2. Cellular Organization

Three classes of myosins:

Myosin I

Myosin II

Myosin V

TLS Online TPP Program

#Id: 8380

#Unit 2. Cellular Organization

single head domain

Function- Membrane association, endocytosis