TLS Online TPP Program

#Id: 9100

#Unit 4. Cell Communication and Cell Signaling

In response to activation of acetylcholine GPCRs, PLC, and the elevation in cytosolic Ca²+, Nitric oxide is synthesized in endothelial cells.

TLS Online TPP Program

#Id: 9101

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 9102

#Unit 4. Cell Communication and Cell Signaling

NO diffuses locally through tissues and activates an

intracellular NO receptor with guanylyl cyclase

activity in nearby smooth muscle cells

TLS Online TPP Program

#Id: 9103

#Unit 4. Cell Communication and Cell Signaling

Resulting rise in cGMP activates protein kinase G leading to relaxation of the muscle and vasodilation

TLS Online TPP Program

#Id: 9299

#Unit 4. Cell Communication and Cell Signaling

Rod cells sense light with the aid of a light-sensitive GPCR called rhodopsin.

TLS Online TPP Program

#Id: 9300

#Unit 4. Cell Communication and Cell Signaling

Rhodopsin has two components: 

Opsin protein, member of the GPCR A family 

11-cis-retinal light-absorbing pigment