Most mRNAs decay stochastically (like the decay of radioactive isotopes), and as a result mRNA stability is usually expressed as a half- life (t½).

TLS Online TPP Program

#Id: 8882

#Unit 2. Cellular Organization

The Aurora kinase family members Aurora A and Aurora B play key roles in mitotic spindle formation and in ensuring that chromosomes attach correctly to the mitotic spindle so that they are segregated accurately during mitosis.

TLS Online TPP Program

#Id: 8883

#Unit 2. Cellular Organization

Once mitotic CDKs are activated at the end of G2 , they phosphorylate specific serine residues in all 3 nuclear lamins.

TLS Online TPP Program

#Id: 8884

#Unit 2. Cellular Organization

This phosphorylation, together with phosphorylation of lamin B by protein kinase C, causes depolymerization of the lamin intermediate filaments.

TLS Online TPP Program

#Id: 8885

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 8886

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 8887

#Unit 2. Cellular Organization

The mitotic CDKs phosphorylate specific nucleoporins, which causes nuclear pore complexes to dissociate during prophase.