TLS Online TPP Program

#Id: 6776


SR Proteins, in its phosphorylated form, the SR protein initially binds to nascent pre-mRNA. When 3′ cleavage and polyadenylation are completed, the adapter protein is dephosphorylated by a specific nuclear protein phosphatase that is essential for mRNP export. Only the dephosphorylated adapter protein can bind the mRNP exporter, thereby coupling mRNP export to correct polyadenylation.





#Unit 3. Fundamental Processes #mRNA stability, transport, CRISPR, miRNA & siRNA #Part B Pointers