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The miRNAs used in RNAi are produced as large RNA primary transcripts called pri-miRNA that are self-complementary and can automatically fold into a double-strand hairpin structure.


#Unit 3. Fundamental Processes #mRNA stability, transport, CRISPR, miRNA & siRNA #Part B Pointers
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#Unit 2. Cellular Organization

In Golgi complex
Arp2/3-dependent assembly of actin occur by an NPF WHAMM participating in membrane traffic from the ER to golgi

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#Id: 5182

#Unit 7. System Physiology – Animal

During formation of a clot the initial event is constriction of the vessel and formation of a temporary hemostatic plug of platelets.


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#Id: 2444

#Unit 3. Fundamental Processes

Different terminators require different levels of rho factor for termination and therefore respond differently to the residual levels of rho factor in the mutants (rho mutants are usually leaky).

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#Id: 10556

#Unit 4. Cell Communication and Cell Signaling

Intrinsic apoptosis pathway
Caspase-8 cleaves the BH3-interacting-domain death agonist (Bid), resulting tBid fragment

TLS Online TPP Program

#Id: 1859

#Unit 3. Fundamental Processes

Sp1 (Mr  80,000) is a transcription activator for a large number of genes in higher eukaryotes. Its DNA binding site, the GC box consensus sequence GGGCGG.

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