Quantitative trait loci (QTLs) - Chromosomal regions containing genes that influence a quantitative trait.

AaBbCc

TLS Online TPP Program

#Id: 1862

#Unit 3. Fundamental Processes

RNA Polymerase I has a Bipartite Promoter

 

TLS Online TPP Program

#Id: 1981

#Unit 3. Fundamental Processes

This structure is called a cap.

TLS Online TPP Program

#Id: 1982

#Unit 3. Fundamental Processes

After transcription initiation, Pol II is paused 30 nucleotides downstream from the initiation site, recruits of the capping enzymes.

TLS Online TPP Program

#Id: 1983

#Unit 3. Fundamental Processes

Capping is done by a dimeric nuclear enzyme which has two subunits and three functions

1. Guanylyl-transferase (GT)

2. Methyltransferase (MT)

TLS Online TPP Program

#Id: 1984

#Unit 3. Fundamental Processes

Structure of cap is

   

TLS Online TPP Program

#Id: 1985

#Unit 3. Fundamental Processes

Binding of the capping enzyme to the TFIIH mediated serine 5–phosphorylated CTD stimulates the activity of the enzyme.