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In human cells, the centromere- specific protein CENP-B is required to initiate modifications of histone H3 (deacetylation of K9 and K14, followed by methylation of K9) that trigger an association with HP1 that leads to the formation of heterochromatin in the region.



#Unit 3. Fundamental Processes #Chromatin Remodelling & Epigenetics #Part B Pointers
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#Unit 4. Cell Communication and Cell Signaling

Rac and RhoA GTPases coordinate changes in cytoskeleton organization and also through Jun-N-terminal kinase (JNK) regulate gene expression

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#Id: 428

#Unit 2. Cellular Organization

Individual nucleosomes can be obtained by treating chromatin with the endonuclease micrococcal nuclease (MNase), which cuts the DNA between nucleosomes, a region known as linker DNA.


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#Id: 6120

#Unit 3. Fundamental Processes

Eukaryotic cells lack MutH and uses Okazaki fragments nick to recognise daughter starnds

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#Id: 4553

#Unit 12. Applied Biology


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#Id: 5699

#Unit 7. System Physiology – Animal

In AV3V region, two structures called osmoreceptors:

subfornical organ
organum vasculosum

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