PRC1 complex binds the methylated nucleosomes through dimeric Pc subunits (CBXs in mammals), each containing a methyl lysine–binding domain (called a chromodomain) specific for methylated H3 lysine 27. 

Binding of the dimeric Pc to neighboring nucleosomes is proposed to condense the chromatin into a structure that inhibits transcription.

TLS Online TPP Program

#Id: 4772

#Unit 5. Developmental Biology

The TBX-35 transcription factor activates mesodermal genes in the MS cell, including pha-4 in the pharynx and hlh-1 in muscles.

TLS Online TPP Program

#Id: 6955

#Unit 8. Inheritance Biology

Reciprocal translocation - Reciprocal exchange of segments between two nonhomologous chromosomes.  Nonreciprocal translocation - Movement of a chromosome segment to a nonhomologous chromosome or chromosomal region without any reciprocal exchange of segments.

TLS Online TPP Program

#Id: 419

#Unit 2. Cellular Organization

Mammalian macroH2A is enriched in the inactive X chromosome in females, which is assembled into a silent, heterochromatic state

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#Id: 3282

#Unit 3. Fundamental Processes

In Escherichia coli,  the complex of MutS and the mismatch-containing DNA recruits MutL, a second protein component of the repair system. 

TLS Online TPP Program

#Id: 7495

#Unit 4. Cell Communication and Cell Signaling

This recombinational event is catalyzed by a set of enzymes, many of which are also involved in nonhomologous end joining (NHEJ) DNA repair functions that occur in all cells.