Recruitment of Polycomb repressor complexes (PRC1 and PRC2), which trigger a series of chromosome-wide histone modifications (H2AK119 ubiquitination, H3K27 methylation, H4K20 methylation, and H4 deacetylation). Late in the process, an inactive X-specific histone variant, macroH2A

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#Id: 6929

#Unit 8. Inheritance Biology

Deletions can be detected cytologically by studying the banding patterns in stained chromosomes. 

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#Id: 6930

#Unit 8. Inheritance Biology

Large aberrations can be detected by examination of mitotic chromosomes that have been stained with banding agents such as quinacrine or Giemsa.

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#Id: 6931

#Unit 8. Inheritance Biology

hCONDEL - Deletions within the human genome containing sequences that are highly conserved among closely related relatives.

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#Id: 6932

#Unit 8. Inheritance Biology

hCONDELs - Responsible for the anatomical and behavioral differences between humans, chimpanzees and other varieties of mammals like ape or monkeys

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#Id: 6933

#Unit 8. Inheritance Biology

Inversions

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#Id: 6934

#Unit 8. Inheritance Biology

Chromosome inversion, in which a chromosome segment is inverted—turned 180 degrees.