UHRF1 also interacts with methylated histone H3, which connects the maintenance of DNA methylation with the stabilization of heterochromatin structure

TLS Online TPP Program

#Id: 3203

#Unit 3. Fundamental Processes

Excision systems remove one strand of DNA at the site of damage and then replace it.

TLS Online TPP Program

#Id: 8882

#Unit 2. Cellular Organization

The Aurora kinase family members Aurora A and Aurora B play key roles in mitotic spindle formation and in ensuring that chromosomes attach correctly to the mitotic spindle so that they are segregated accurately during mitosis.

TLS Online TPP Program

#Id: 9631

#Unit 4. Cell Communication and Cell Signaling

Monomeric Ras protein 

(∼170 amino acids) belongs to the GTPase superfamily of

intracellular switch proteins

TLS Online TPP Program

#Id: 6011

#Unit 3. Fundamental Processes

Hence Cdc6 and Cdt1 are the key licensing factors and helicase loading proteins.

TLS Online TPP Program

#Id: 6363

#Unit 2. Cellular Organization

There are 4 genes (I, Z, Y, A), 2 Promoters and 3 lac operators in Lac operon

The major O1 lac operator lies adjacent to promoter

The O1 operator extends from position -5 just upstream of the mRNA start point to position +21 within the transcription unit.