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TLS Online TPP Program

#Id: 6946

In Paracentric inversion - a single crossover takes place in the inverted region an unusual structure results



#Unit 8. Inheritance Biology #Structural and numerical alterations of chromosomes #Part B Pointers
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TLS Online TPP Program

#Id: 9647

#Unit 4. Cell Communication and Cell Signaling

Constitutively active Raf kinase
a glutamic acid substitution for the valine at position 600
TLS Online TPP Program

#Id: 9648

#Unit 4. Cell Communication and Cell Signaling

MEK is a dual-specificity protein kinase
phosphorylates its target proteins on both tyrosine and serine/threonine
TLS Online TPP Program

#Id: 9649

#Unit 4. Cell Communication and Cell Signaling

In humans, there are three RAS, three Raf, two MEK, and two MAP proteins.
TLS Online TPP Program

#Id: 9650

#Unit 4. Cell Communication and Cell Signaling

Mammalian MAP kinases include  Jun N-terminal kinases and p38 kinases, which are activated by signaling pathways in response to various types of stresses
TLS Online TPP Program

#Id: 9651

#Unit 4. Cell Communication and Cell Signaling

Phosphorylation by MEK at Y-185 and T-183 in activation loop of MAP kinase leads to a marked conformational change & promotes MAP kinase activation and dimerization.
TLS Online TPP Program

#Id: 9652

#Unit 4. Cell Communication and Cell Signaling