Unpaired protein activates the JAK-STAT pathway in the adjacent germ stem cells to specify their self-renewal

TLS Online TPP Program

#Id: 3196

#Unit 4. Cell Communication and Cell Signaling

Mutations in three broad classes of genes play key roles in cancer induction: 

Proto-oncogenes genes
Tumor-suppressor genes
Genome maintenance genes

TLS Online TPP Program

#Id: 3197

#Unit 4. Cell Communication and Cell Signaling

Dominant gain-of-function mutations in proto-oncogenes and recessive loss-of-function mutations in tumor-suppressor genes are oncogenic.

TLS Online TPP Program

#Id: 3208

#Unit 4. Cell Communication and Cell Signaling

Mutations in three broad classes of genes play key roles in cancer induction:
Proto-oncogenes genes
Tumor-suppressor genes
Genome maintenance genes

TLS Online TPP Program

#Id: 3209

#Unit 4. Cell Communication and Cell Signaling

Dominant gain-of-function mutations in proto-oncogenes and recessive loss-of-function mutations in tumor-suppressor genes are oncogenic.

TLS Online TPP Program

#Id: 3210

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 3211

#Unit 4. Cell Communication and Cell Signaling

Three mechanisms can produce oncogenes from the corresponding proto-oncogenes:
Point mutation
Chromosomal translocation
Amplification