A replicon has origin at which replication is initiated. It may also have a terminus at which replication stops.

TLS Online TPP Program

#Id: 3640

#Unit 3. Fundamental Processes

Class II AATS are generally dimer and rarely tetramer.

TLS Online TPP Program

#Id: 3641

#Unit 3. Fundamental Processes

Class I and Class II aminoacyl–tRNA synthetases differ in several ways: Structural motifs, Anticodon recognition, Site of aminoacylation, Amino acid specificity.

TLS Online TPP Program

#Id: 3642

#Unit 3. Fundamental Processes

The Class I enzymes share two homologous polypeptide segments that are components of a dinucleotide-binding fold (Rossmann fold, which is also present in many NAD+- and ATP-binding proteins.

TLS Online TPP Program

#Id: 3643

#Unit 3. Fundamental Processes

The Class II synthetases lack the foregoing sequences but have three other sequences in common.

TLS Online TPP Program

#Id: 3644

#Unit 3. Fundamental Processes

Many Classes I aaRSs must recognize the anticodon to aminoacylate their cognate tRNAs.

TLS Online TPP Program

#Id: 3645

#Unit 3. Fundamental Processes

Several Class II enzymes do not interact with their bound tRNA’s anticodon.