One individual, however, expresses only a small number of these molecules—up to six different class I molecules and 12 or more different class II molecules.

TLS Online TPP Program

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#Unit 3. Fundamental Processes

These polymerases are template-dependent, they incorporate nucleotides in a manner that is independent of base pairing.

TLS Online TPP Program

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#Unit 3. Fundamental Processes

Human member of the Y family of translesion polymerases (DNA Pol n) correctly inserts two A residues opposite a thymine dimer. 

TLS Online TPP Program

#Id: 6156

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 6157

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 6158

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 6159

#Unit 3. Fundamental Processes

Ubiquitination of the sliding clamp is therefore a distress signal that recruits a translesion polymerase to rescue a replication machine that is stalled at a site of DNA damage.