Genetic Disorder

An autosomal recessive condition affects 1 newborn in 10,000 in a random mating population without any  disruptive acting force. What is the approximate expected frequency of carriers in this population?

1 in 1000 newborns

1 in 500 newborns

1 in 100 newborns

1 in 50 newborns

TLS Online TPP Program

#Id: 2381

#Unit 3. Fundamental Processes

Brr2 facilitates U1 and U4 release

TLS Online TPP Program

#Id: 2382

#Unit 3. Fundamental Processes

Prp2 is responsible for the activation of the spliceosome Prp22 helps the release of the mature mRNA from the spliceosome

TLS Online TPP Program

#Id: 2383

#Unit 3. Fundamental Processes

Prp22 helps the release of the mature mRNA from the spliceosome, makes splicing irreversible.

TLS Online TPP Program

#Id: 2384

#Unit 3. Fundamental Processes

More than 90% of the genes expressed in mammals are alternatively spliced

TLS Online TPP Program

#Id: 2385

#Unit 3. Fundamental Processes

 Five ways to splice an RNA

TLS Online TPP Program

#Id: 2386

#Unit 3. Fundamental Processes

Steric Hindrance and Combinations of Major and Minor Splice Sites are major reasons behind alternative splicing (Mutually Exclusive Splicing)