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TLS Online TPP Program

#Id: 7455

RegA is activated by phosphorylation of an aspartate in its response regulator domain.


#Unit 5. Developmental Biology #Cell aggregation and differentiation in Dictyostelium #Part B Pointers
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TLS Online TPP Program

#Id: 8598

#Unit 2. Cellular Organization

Labile factors called cyclins drive the progression of cells through different stages of the cell cycle by binding to CDKs.
TLS Online TPP Program

#Id: 8599

#Unit 2. Cellular Organization

Cells commit to a new cell division at a specific point in G1 known as START or the restriction point.
TLS Online TPP Program

#Id: 8600

#Unit 2. Cellular Organization

R-factor 
In mammalian cells - cyclin D 
In yeast - Cln3
TLS Online TPP Program

#Id: 8601

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8602

#Unit 2. Cellular Organization

cyclin-CDK complexes preferentially phosphorylate
serine and threonine residues when they are found within the consensus sequence:
[S/T]PX[R/K]K 
TLS Online TPP Program

#Id: 8603

#Unit 2. Cellular Organization

G1 Cyclin–CDKs
In human - cyclin D-CDK 4 
cyclin D-CDK 6
In budding yeast - CIn 3-Cdc 28