The two β pleated sheets in each domain are held together by hydrophobic interactions and the conserved disulfide bond.  The three loops of each variable domain show considerable variation in length and amino acid sequence; these hyper variable regions  make up the antigen-binding site. 

TLS Online TPP Program

#Id: 10080

#Unit 4. Cell Communication and Cell Signaling

Integrins bind extracellular matrix (ECM) glycoproteins, 

1. Laminins  

2. Collagens 

3. Fibronectin

4. Vitronectin

TLS Online TPP Program

#Id: 2487

#Unit 13. Methods in Biology

Acrylamide gels can be made with a content of between 3% and 30% acrylamide Low concentration are used to where free movement of the proteins is required without any noticeable frictional effect such as flat-bed isoelectric focusing or the stacking gel system of an SDS–polyacrylamide gel.

TLS Online TPP Program

#Id: 4788

#Unit 5. Developmental Biology

P2 cell establishes the

dorsal-ventral axis of C. elegans and confers on the ABp blastomere a fate different from that of its sister cell.

TLS Online TPP Program

#Id: 3210

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 902

#Unit 13. Methods in Biology

Flow cytometry or FACS is the sine qua non (without which, nothing) of the modern immunologist’s toolbox.