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TLS Online TPP Program

#Id: 7482

IgD

B cell antigen receptor and may participate in B cell maturation.Exact function is still unclear, IgD may be involved in humoral immune responses by regulating B cell selection and homeostasis.

#Unit 4. Cell Communication and Cell Signaling #Antibody #Part B Pointers
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TLS Online TPP Program

#Id: 8327

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8328

#Unit 2. Cellular Organization

Hydrolysis of the bound nucleotide reduces the binding affinity of the subunit for neighbouring subunits and makes it more likely to dissociate from each end of the filament.
T form that adds to the filament and the D form that leaves.
TLS Online TPP Program

#Id: 8329

#Unit 2. Cellular Organization

Treadmilling
Because the critical concentrations for the two ends are different, at steady state the free ATP–G-actin will be intermediate between Cc+ and Cc - , so the (+)end will grow and the (-)end will lose subunits.
TLS Online TPP Program

#Id: 8330

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8331

#Unit 2. Cellular Organization

Cytochalasin D, 
a fungal alkaloid, depolymerizes actin filaments by binding to the (+) end of F-actin.
TLS Online TPP Program

#Id: 8332

#Unit 2. Cellular Organization

Latrunculin, 
a toxin secreted by sponges, binds and sequesters G-actin