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TLS Online TPP Program

#Id: 7506

RAG1 subunit and contains two aspartic acid residues and one glutamic acid residue (D600, D708, and E962, respectively). This active site “DDE motif” is found in many enzymes that cleave DNA



#Unit 4. Cell Communication and Cell Signaling #V(D)J Recombination #Part B Pointers
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TLS Online TPP Program

#Id: 10341

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 10342

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 10343

#Unit 4. Cell Communication and Cell Signaling

The heavy chain is then expressed on the cell surface in combination with the surrogate light chain, which is made up of VpreB and λ5. 
TLS Online TPP Program

#Id: 10344

#Unit 4. Cell Communication and Cell Signaling

B- cell maturation
TLS Online TPP Program

#Id: 10345

#Unit 4. Cell Communication and Cell Signaling

T1 and T2 Transitional B Cells
TLS Online TPP Program

#Id: 10346

#Unit 4. Cell Communication and Cell Signaling

T1 cells are mIgMhi, mIgD -/lo, CD21-, CD23-, CD24+, and CD93+. 
T2 cells differ from T1 cells in having higher levels of mIgD and in expressing CD21 and CD23.