Nurturing Life Sciences
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#Unit 5. Developmental Biology
In primary neurulation,
cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate into the body, and separate from the surface ectoderm to form an underlying hollow tube.
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Primary neurulation forms the anterior portion of the neural tube
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Secondary neurulation forms the posterior portion of the neural tube
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In birds, primary neurulation generates the neural tube anterior to the hindlimbs.
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In mammals, secondary neurulation begins at the level of the sacral vertebrae of the tail.