Nurturing Life Sciences
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#Unit 3. Fundamental Processes
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Global genome repair and transcription-coupled repair differ in their mechanisms of damage recognition (XPC vs. RNA polymerase II).
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transitions, which are pyrimidine-to-pyrimidine and purine-to-purine substitutions, such as T to C and A to G;
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transversions, which are pyrimidine-to-purine and purine-to-pyrimidine substitutions, such as T to G or A and A to C or T.
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Mutations that alter a single nucleotide are called point mutations.