Nuclear-export signal (NES)

ribonuclear protein complexes that shuttle between the nucleus and the cytoplasm. Such shuttling proteins contain NES.

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#Unit 7. System Physiology – Animal

The heart consists of two kinds of muscle cells:

Contractile cells

Conducting cells

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#Unit 7. System Physiology – Animal

Contractile cells constitute the majority of atrial & ventricular tissues.

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#Unit 7. System Physiology – Animal

Conducting cells constitute tissues of the SA node, the atrial internodal tracts, the AV node, the bundle of His, & the Purkinje system.

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#Unit 7. System Physiology – Animal

Conducting cells are specialized muscle cells which function to rapidly spread action potentials over the entire myocardium.

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#Unit 7. System Physiology – Animal

The action potential spreads throughout the myocardium in the following sequence:

SA node  Atrial internodal tracts and atria  AV node  Bundle of His  Purkinje system  Ventricles

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#Unit 7. System Physiology – Animal

Myocardial fibers have a resting membrane potential of approximately –90 mV.