Nurturing Life Sciences
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#Unit 3. Fundamental Processes
Alkylating agents induce all types of mutations, including transitions, transversions, frameshifts, and even chromosome aberrations.
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#Unit 2. Cellular Organization
Fold potential (measured in negative units) is high (more negative) in introns, and low (more positive) in exons.
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Leaky Expression cannot happen in P- and Z- mutants
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In healthy mitochondria, PINK1 resides in the mitochondrial matrix.
In damaged or dysfunctional mitochondria, PINK1 resides on the outer mitochondrial membrane, where it recruits cytosolic Parkin.
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Exon sequences are conserved by the negative selection of individuals in which the sequences have changed