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TLS Online TPP Program

#Id: 809

In the bacterial genome, the minimum length of promoter that could provide an adequate signal is 12 bp.  The minimum length required for unique recognition increases with the size of genome, a problem in eukaryotic genomes.

#Unit 3. Fundamental Processes #Basics of Prokaryotic Transcription #Part B Pointers
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TLS Online TPP Program

#Id: 1678

#Unit 4. Cell Communication and Cell Signaling

Multiple gene segments exist at heavy (V, D, and J) and light-chain (V and J) loci.
TLS Online TPP Program

#Id: 1679

#Unit 4. Cell Communication and Cell Signaling

Junctional diversity- P and N nucleotides  addition
TLS Online TPP Program

#Id: 1680

#Unit 4. Cell Communication and Cell Signaling

P nucleotide addition results when the DNA hairpin at the coding joint is cleaved asymmetrically.
TLS Online TPP Program

#Id: 1681

#Unit 4. Cell Communication and Cell Signaling

Non - templated N nucleotide addition in heavy chains results from TdT activity.
TLS Online TPP Program

#Id: 1682

#Unit 4. Cell Communication and Cell Signaling

Exonuclease trimming sometimes occurs at the VDJ and VJ junctions, causing loss of nucleotides.
TLS Online TPP Program

#Id: 1683

#Unit 4. Cell Communication and Cell Signaling

Combinatorial diversity: The same heavy chain can combine with different light chain