TLS Online TPP Program

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#Unit 5. Developmental Biology

Commitment

At this stage the cell or tissue does not appear phenotypically different from its uncommitted state, its developmental fate has become restricted.

TLS Online TPP Program

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#Unit 5. Developmental Biology

Stages of commitment- 

1- Specification 

2- Determination

TLS Online TPP Program

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#Unit 5. Developmental Biology

Cell Specification

cells become specified to a specific fate

TLS Online TPP Program

#Id: 88

#Unit 5. Developmental Biology

Specification (capable of being altered)

It is a labile phase, so it is not fixed.

TLS Online TPP Program

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#Unit 5. Developmental Biology

There are three different modes of cell specification: 

1. Autonomous

2. Conditional

3. Syncytial

TLS Online TPP Program

#Id: 90

#Unit 5. Developmental Biology

Autonomous Specification

Cell “knows” very early what it is to become without interacting with other cells