Dispersal is the movement of individuals from one area to another.

Dispersal involves individuals leaving their habitat of origin—where a seed was made or where a squirrel was born—and typically not returning.

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#Unit 4. Cell Communication and Cell Signaling

Chromosomal translocation 

That fuses two genes together to produce a hybrid gene encoding a chimeric protein whose activity is constitutive

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#Id: 10451

#Unit 4. Cell Communication and Cell Signaling

Chromosomal translocation 

That brings a growth regulatory gene under the control of alternative enhancers that cause inappropriate expression of the gene

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#Id: 10452

#Unit 4. Cell Communication and Cell Signaling

Philadelphia chromosome generated by a translocation

between chromosomes 22 and 9

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#Unit 4. Cell Communication and Cell Signaling

Translocation between chromosomes 22 and 9 form new oncogenic fusion protein - BCR-ABL hybrid protein kinase

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#Id: 10454

#Unit 4. Cell Communication and Cell Signaling

BCR-ABL fusion protein is a constitutively active

kinase that phosphorylates multiple signal-transducing proteins. 

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#Id: 10455

#Unit 4. Cell Communication and Cell Signaling

Chronic myelogenous leukemia, 

a common leukemia in humans, associated with the Philadelphia chromosome