Nurturing Life Sciences
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#Unit 5. Developmental Biology
The dorsoventral patterning of the early Drosophila embryo is controlled by a regulatory protein called Dorsal.
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In mammals, the conversion of the genital ridge into the bipotential gonad requires, among others, the Sf1, Wt1, and Lhx9 genes.
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In mammals, the bipotential gonad appears to be moved into the female pathway (ovary development) by the Foxl2, Wnt4, and Rspo1 genes.
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In mammals, the bipotential gonad appears to be moved into the male pathway (testis development) by the Sry gene (on the Y chromosome), which triggers the activity of Sox9.