Once sufficient Cln3 is synthesized from its mRNA, Cln3-CDK complexes phosphorylate and inactivate the transcriptional repressor Whi5.

TLS Online TPP Program

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#Unit 7. System Physiology – Animal

Hair processes provide a mechanism for generating changes in membrane potential proportional to the

direction and distance the hair moves

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#Id: 5673

#Unit 7. System Physiology – Animal

The resting membrane potential of the hair cells is about

–60 mV. 

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#Id: 5674

#Unit 7. System Physiology – Animal

Vibration of the organ of Corti causes bending of stereocilia on the hair cells by a shearing force as the cilia push against the tectorial membrane

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#Id: 5675

#Unit 7. System Physiology – Animal

When the shorter stereocilia are pushed toward the taller ones, the open time of cation channels is increased

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#Id: 5676

#Unit 7. System Physiology – Animal

K+ & Ca2+ enter via the channel and produce depolarization

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#Id: 5677

#Unit 7. System Physiology – Animal

When the stereocilia are pushed toward the kinocilium, the membrane potential is decreased to about –50 mV.