Fission yeast cells carrying a CDK1 mutation in which the tyrosine-15 residue is replaced by phenylalanine

show the same premature mitotic CDK activation and entry into mitosis.

TLS Online TPP Program

#Id: 10016

#Unit 4. Cell Communication and Cell Signaling

Cytosolic complex is bound to a microtubule by the kinesin-related motor protein Costal-2 (Cos2).

TLS Online TPP Program

#Id: 696

#Unit 3. Fundamental Processes

1. The small fragment (35 kD) possesses a 5’– 3’ exonucleolytic activity, which excises small groups of nucleotides, up to 10 bases at a time.

2. This activity is coordinated with the synthetic/ proofreading activity. 

3. It provides DNA polymerase I with a unique ability to start replication in vitro at a nick in DNA.

TLS Online TPP Program

#Id: 8982

#Unit 11. Evolution and Behavior

The introduction of new genetic variation into an inbred population, called genetic rescue.

TLS Online TPP Program

#Id: 8913

#Unit 2. Cellular Organization

APC/CCdc²⁰ is inhibited by a checkpoint pathway that ensures that anaphase is not initiated until all chromosomes have achieved proper attachment to the mitotic apparatus.

TLS Online TPP Program

#Id: 3350

#Unit 3. Fundamental Processes

Methyltransferase catalyzes the transfer of the methyl group on O6 -methylguanine to a cysteine residue on the enzyme, thereby restoring the normal G in DNA.