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TLS Online TPP Program

#Id: 8921

At the same time, Plk1 phosphorylates the Rho-GAP component, to form an active Centralspindlin-Ect2 complex. 

#Unit 2. Cellular Organization #CELL CYCLE #Part B Pointers
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TLS Online TPP Program

#Id: 9310

#Unit 4. Cell Communication and Cell Signaling

In the dark, 
membrane potential of a rod cell is about −30 mV (Depolarized state)
Rod cells release neurotransmitters (glutamate) constantly
TLS Online TPP Program

#Id: 9311

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 9312

#Unit 4. Cell Communication and Cell Signaling

Depolarized state of a resting rod cell is due to the presence of a large number of open nonselective ion channels that admit both Na+ & Ca2+ into the cell
TLS Online TPP Program

#Id: 9313

#Unit 4. Cell Communication and Cell Signaling

Nonselective cation channels open in response to binding of the second messenger cGMP (cGMP-gated channels)
TLS Online TPP Program

#Id: 9314

#Unit 4. Cell Communication and Cell Signaling

3 or 4 cGMP molecules must bind to each channel in order to open it; because of this cooperative allosteric interaction, channel opening is very sensitive to small changes in cGMP levels.
TLS Online TPP Program

#Id: 9315

#Unit 4. Cell Communication and Cell Signaling

In resting rod cells high cGMP concentration generated from GTP catalyzed by guanylyl cyclase.