Nonsynonymous mutations, on the other hand, alter the amino acid sequence of the protein and in many cases are detrimental to the fitness of the organism, so most of these mutations are eliminated by natural selection.

TLS Online TPP Program

#Id: 6669

#Unit 3. Fundamental Processes

There are three type of Splicing signals 

 Major U2-type or GU-AG introns

Minor U12-type or AU-AC introns

Minor U12-type with GU-AG introns (hybrid type)

TLS Online TPP Program

#Id: 6670

#Unit 3. Fundamental Processes

UACUAAC is branch point sequence for U2 type introns CCUUAAC is branch point sequence for U12 type introns

TLS Online TPP Program

#Id: 6671

#Unit 3. Fundamental Processes

Major U2-type or GU-AG introns

TLS Online TPP Program

#Id: 6672

#Unit 3. Fundamental Processes

Minor U12-type with GU-AG introns (hybrid type)

TLS Online TPP Program

#Id: 6673

#Unit 3. Fundamental Processes

Splice sites are directional in nature. 5’ splice site -the left, or donor, site and the 3’ splice site - right, or acceptor, site

TLS Online TPP Program

#Id: 6674

#Unit 3. Fundamental Processes