The current record holder is the gene Dscam in Drosophila. Alternative splicing of its 95 exons could potentially produce more than 38,000 kinds of proteins from this single gene.

TLS Online TPP Program

#Id: 360

#Unit 1. Molecules and their Interaction Relevant to Biology

The cytosolic isozymes has two distinct function, It catalyzes the conversion of citrate to isocitrate, providing the substrate for a cytosolic isocitrate dehydrogenase that generates NADPH as reducing power for fatty acid synthesis and other anabolic processes in the cytosol. It also has a role in cellular iron homeostasis

TLS Online TPP Program

#Id: 363

#Unit 1. Molecules and their Interaction Relevant to Biology

When cellular iron concentrations return to normal levels, IRP1 is converted to aconitase, and IRP2 undergoes proteolytic degradation, ending the low-iron response.

TLS Online TPP Program

#Id: 364

#Unit 1. Molecules and their Interaction Relevant to Biology

Pyruvate kinase acts in the nucleus to regulate the transcription of genes that respond to thyroid hormone. Glyceraldehyde 3-phosphate dehydrogenase moonlights both as uracil DNA glycosylase, effecting the repair of damaged DNA, and as a regulator of histone H2B transcription. 

TLS Online TPP Program

#Id: 366

#Unit 1. Molecules and their Interaction Relevant to Biology

The enzyme that catalyzes this reversible reaction is called succinyl-CoA synthetase or succinic thiokinase

TLS Online TPP Program

#Id: 8674

#Unit 1. Molecules and their Interaction Relevant to Biology

TLS Online TPP Program

#Id: 8675

#Unit 1. Molecules and their Interaction Relevant to Biology

Insulin activates

GluT4

Hexokinase

Glycogen Synthase