Nurturing Life Sciences
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#Unit 2. Cellular Organization
The nucleosome has an approximate twofold axis of symmetry, called the dyad axis.
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DNA enters at 1 o’clock and exits at just short of 11 o’clock on one axis and they change time after 180 degree rotation
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Of the 147 bp of DNA included in the structure, the histone-fold regions of the H3.H4 tetramer interact with the central 60 bp.
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The H3.H4 tetramer forms the top half of the histone octamer. Histone H3.H4 tetramers occupy a key position in the nucleosome by binding the middle and both ends of the DNA
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The two H2A.H2B dimers each associate with 30 bp of DNA on either side of the central 60 bp of DNA bound by H3 and H4.