Effects of inbreeding on Japanese children

TLS Online TPP Program

#Id: 3694

#Unit 2. Cellular Organization

Genes are not uniformly distributed in the genome.

Regions longer than 500 kb where there are no ORFs called as deserts

The most gene-rich chromosomes have 10% of their sequences as deserts. So overall, 20% of the human genome consists of deserts that have no protein coding genes.

TLS Online TPP Program

#Id: 3280

#Unit 3. Fundamental Processes

MutS embraces the mismatch-containing DNA, inducing a pronounced kink in the DNA and a conformational change in MutS itself.

TLS Online TPP Program

#Id: 6024

#Unit 3. Fundamental Processes

DNA polymerase a is unusual because it has the ability to initiate a new strand. It is used to initiate both the leading and lagging strands. 

The enzyme exists as a complex consisting of a 180-kD catalytic (DNA polymerase) subunit, which is associated with three other subunits: the B subunit that appears necessary for assembly, and two small subunits that provide the primase (RNA polymerase) activity.  It has dual capacity to prime and extend chains, this complex is often called pol a/primase.

TLS Online TPP Program

#Id: 9504

#Unit 6. System Physiology – Plant

Xanthomonas, produces TAL (transcription activator‐like) effectors contribute to disease formation or trigger defense by binding host DNA and activating effector‐specific host genes.

TLS Online TPP Program

#Id: 1484

#Unit 4. Cell Communication and Cell Signaling

Monomers and dimers of p53, exists in the cytoplasm.